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TitleLegionella pneumophila DHDPS: The First Case of Non-Lysine Inhibition in a Gram-Negative Pathogen
Journal, issue, pagesTo be Published
Publish dateNov 23, 2013 (structure data deposition date)
AuthorsSiddiqui, T. / Paxman, J.J. / Dogovski, C. / Panjikar, S. / Perugini, M.A.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.65 Å
Structure data

PDB-4nq1:
Legionella pneumophila dihydrodipicolinate synthase with first substrate pyruvate bound in the active site
Method: X-RAY DIFFRACTION / Resolution: 1.65 Å

Chemicals

ChemComp-MRD:
(4R)-2-METHYLPENTANE-2,4-DIOL / precipitant*YM

ChemComp-CL:
Unknown entry

ChemComp-MG:
Unknown entry

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

ChemComp-HOH:
WATER

Source
  • legionella pneumophila (bacteria)
KeywordsLYASE / TIM BARREL / LYSINE BIOSYNTHESIS / DIHYDRODIPICOLINATE SYNTHESIS / PYRUVATE

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