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-Structure paper
Title | Rational design of urea-based glutamate carboxypeptidase II (GCPII) inhibitors as versatile tools for specific drug targeting and delivery. |
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Journal, issue, pages | Bioorg. Med. Chem., Vol. 22, Page 4099-4108, Year 2014 |
Publish date | Nov 2, 2013 (structure data deposition date) |
Authors | Tykvart, J. / Schimer, J. / Barinkova, J. / Pachl, P. / Postova-Slavetinska, L. / Majer, P. / Konvalinka, J. / Sacha, P. |
External links | Bioorg. Med. Chem. / PubMed:24954515 |
Methods | X-ray diffraction |
Resolution | 1.63 - 2.31 Å |
Structure data | PDB-4ngm: PDB-4ngn: PDB-4ngp: PDB-4ngq: PDB-4ngr: PDB-4ngs: PDB-4ngt: |
Chemicals | ChemComp-NAG: ChemComp-ZN: ChemComp-CL: ChemComp-CA: ChemComp-JB7: ChemComp-HOH: ChemComp-J96: ChemComp-J31: ChemComp-J37: ChemComp-J21: ChemComp-J34: ChemComp-NA: ChemComp-J42: |
Source |
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Keywords | HYDROLASE/HYDROLASE INHIBITOR / hydrolase / glutamate carboxypeptidase II / PSMA / NAALADASE / urea-based inhibitor / caboxypeptidase / glycoprotein / metallopeptidase / HYDROLASE-HYDROLASE INHIBITOR complex / trasmembrane |