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Structure paper

TitleCrystal structures of human transthyretin complexed with glabridin
Journal, issue, pagesJ. Med. Chem., Vol. 57, Page 1090-1096, Year 2014
Publish dateOct 17, 2013 (structure data deposition date)
AuthorsYokoyama, T. / Kosaka, Y. / Mizuguchi, M.
External linksJ. Med. Chem. / PubMed:24422526
MethodsX-ray diffraction
Resolution1.6 - 2.001 Å
Structure data

PDB-4n85:
Crystal structure of human transthyretin
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-4n86:
Crystal structure of human transthyretin complexed with glabridin
Method: X-RAY DIFFRACTION / Resolution: 2.001 Å

PDB-4n87:
Crystal structure of V30M mutant human transthyretin complexed with glabridin
Method: X-RAY DIFFRACTION / Resolution: 1.794 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-GBJ:
4-[(3R)-8,8-dimethyl-3,4-dihydro-2H,8H-pyrano[2,3-f]chromen-3-yl]benzene-1,3-diol

Source
  • homo sapiens (human)
KeywordsTRANSPORT PROTEIN / thyroxine binding / transporter

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