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TitleVestigialization of an allosteric switch: genetic and structural mechanisms for the evolution of constitutive activity in a steroid hormone receptor.
Journal, issue, pagesPLoS Genet, Vol. 10, Page e1004058-e1004058, Year 2014
Publish dateOct 4, 2013 (structure data deposition date)
AuthorsBridgham, J.T. / Keay, J. / Ortlund, E.A. / Thornton, J.W.
External linksPLoS Genet / PubMed:24415950
MethodsX-ray diffraction
Resolution2.605 Å
Structure data

PDB-4n1y:
Crystal Structure of the Pacific Oyster Estrogen Receptor Ligand Binding Domain
Method: X-RAY DIFFRACTION / Resolution: 2.605 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • crassostrea gigas (Pacific oyster)
KeywordsTRANSCRIPTION / estrogen / Nuclear Hormone Receptor / Endocrine signaling

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