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-Structure paper
Title | Structural Basis for Autoinhibition of CTP:Phosphocholine Cytidylyltransferase (CCT), the Regulatory Enzyme in Phosphatidylcholine Synthesis, by Its Membrane-binding Amphipathic Helix. |
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Journal, issue, pages | J. Biol. Chem., Vol. 289, Page 1742-1755, Year 2014 |
Publish date | Sep 23, 2013 (structure data deposition date) |
![]() | Lee, J. / Taneva, S.G. / Holland, B.W. / Tieleman, D.P. / Cornell, R.B. |
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Methods | X-ray diffraction |
Resolution | 3 - 8 Å |
Structure data | ![]() PDB-4mvc: ![]() PDB-4mvd: |
Chemicals | ![]() ChemComp-CDC: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSFERASE / Rossmann Fold / Amphipathic helix / Lipid Membrane Binding / Cytidine 5 -diphosphocholine synthesis / Phosphatidylcholine homeostasis / Lipid Membrane Surface / Endoplasmic Reticulum / Nucleus / Four-helix bundle / Cytidine 5'-diphosphocholine synthesis |