+Search query
-Structure paper
Title | Structural and functional analysis of g protein-coupled receptor kinase inhibition by paroxetine and a rationally designed analog. |
---|---|
Journal, issue, pages | Mol. Pharmacol., Vol. 85, Page 237-248, Year 2014 |
Publish date | Jun 18, 2013 (structure data deposition date) |
![]() | Homan, K.T. / Wu, E. / Wilson, M.W. / Singh, P. / Larsen, S.D. / Tesmer, J.J. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.32 - 2.4 Å |
Structure data | ![]() PDB-4l9i: ![]() PDB-4mk0: |
Chemicals | ![]() ChemComp-8PR: ![]() ChemComp-MES: ![]() ChemComp-CL: ![]() ChemComp-HOH: ![]() ChemComp-GOL: ![]() ChemComp-29X: |
Source |
|
![]() | Transferase / membrane protein/inhibitor / AGC family kinase / SER/THR KINASE / RGS HOMOLOGY DOMAIN / G PROTEIN COUPLED RECEPTOR KINASE / GRK / GRK1 / RHODOPSIN KINASE / SSRI / HYDROLYASE / GPCR / PHOSPHORYLATION / membrane protein-inhibitor complex / SIGNALING PROTEIN/inhibitor / INHIBITOR COMPLEX / PROTEIN KINASE / HYDROLASE / ATP BINDING / PERIPHERAL MEMBRANE PROTEIN / SIGNALING PROTEIN-inhibitor complex |