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| Title | GluK1 antagonists from 6-(tetrazolyl)phenyl decahydroisoquinoline derivatives: in vitro profile and in vivo analgesic efficacy. |
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| Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 23, Page 6463-6466, Year 2013 |
| Publish date | Aug 27, 2013 (structure data deposition date) |
 Authors | Martinez-Perez, J.A. / Iyengar, S. / Shannon, H.E. / Bleakman, D. / Alt, A. / Clawson, D.K. / Arnold, B.M. / Bell, M.G. / Bleisch, T.J. / Castano, A.M. ...Martinez-Perez, J.A. / Iyengar, S. / Shannon, H.E. / Bleakman, D. / Alt, A. / Clawson, D.K. / Arnold, B.M. / Bell, M.G. / Bleisch, T.J. / Castano, A.M. / Del Prado, M. / Dominguez, E. / Escribano, A.M. / Filla, S.A. / Ho, K.H. / Hudziak, K.J. / Jones, C.K. / Mateo, A. / Mathes, B.M. / Mattiuz, E.L. / Ogden, A.M. / Simmons, R.M. / Stack, D.R. / Stratford, R.E. / Winter, M.A. / Wu, Z. / Ornstein, P.L. |
 External links | Bioorg. Med. Chem. Lett. / PubMed:24140446 |
| Methods | X-ray diffraction |
| Resolution | 3 Å |
| Structure data |  PDB-4mf3: |
| Chemicals |  ChemComp-SXI:  ChemComp-HOH: |
| Source |
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 Keywords | SIGNALING PROTEIN / Protein-Ligand Complex / Ligand Gated Ion Channel / Glutamate Receptor / Glutamate binding / none / Membrane |
homo sapiens (human)