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-Structure paper
| Title | Structure-based design and synthesis of potent benzothiazole inhibitors of interleukin-2 inducible T cell kinase (ITK). |
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| Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 23, Page 6331-6335, Year 2013 |
| Publish date | Aug 27, 2013 (structure data deposition date) |
 Authors | Mackinnon, C.H. / Lau, K. / Burch, J.D. / Chen, Y. / Dines, J. / Ding, X. / Eigenbrot, C. / Heifetz, A. / Jaochico, A. / Johnson, A. ...Mackinnon, C.H. / Lau, K. / Burch, J.D. / Chen, Y. / Dines, J. / Ding, X. / Eigenbrot, C. / Heifetz, A. / Jaochico, A. / Johnson, A. / Kraemer, J. / Kruger, S. / Krulle, T.M. / Liimatta, M. / Ly, J. / Maghames, R. / Montalbetti, C.A. / Ortwine, D.F. / Perez-Fuertes, Y. / Shia, S. / Stein, D.B. / Trani, G. / Vaidya, D.G. / Wang, X. / Bromidge, S.M. / Wu, L.C. / Pei, Z. |
 External links | Bioorg. Med. Chem. Lett. / PubMed:24138940 |
| Methods | X-ray diffraction |
| Resolution | 2.113 - 2.67 Å |
| Structure data |  PDB-4mf0:  PDB-4mf1: |
| Chemicals |  ChemComp-29Z:  ChemComp-HOH:  ChemComp-29Y: |
| Source |
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 Keywords | transferase/transferase inhibitor / protein kinase / phosphotransfer catalyst / transferase-transferase inhibitor complex |
homo sapiens (human)