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TitleTranscription inhibition by the depsipeptide antibiotic salinamide A.
Journal, issue, pagesElife, Vol. 3, Page e02451-e02451, Year 2014
Publish dateAug 27, 2013 (structure data deposition date)
AuthorsDegen, D. / Feng, Y. / Zhang, Y. / Ebright, K.Y. / Ebright, Y.W. / Gigliotti, M. / Vahedian-Movahed, H. / Mandal, S. / Talaue, M. / Connell, N. ...Degen, D. / Feng, Y. / Zhang, Y. / Ebright, K.Y. / Ebright, Y.W. / Gigliotti, M. / Vahedian-Movahed, H. / Mandal, S. / Talaue, M. / Connell, N. / Arnold, E. / Fenical, W. / Ebright, R.H.
External linksElife / PubMed:24843001
MethodsX-ray diffraction
Resolution3.902 - 3.948 Å
Structure data

PDB-4mex:
Crystal structure of Escherichia coli RNA polymerase in complex with salinamide A
Method: X-RAY DIFFRACTION / Resolution: 3.902 Å

PDB-4mey:
Crystal structure of Escherichia coli RNA polymerase holoenzyme
Method: X-RAY DIFFRACTION / Resolution: 3.948 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-ZN:
Unknown entry

Source
  • escherichia coli (E. coli)
  • streptomyces sp. (bacteria)
KeywordsTransferase/Antibiotic / RNA polymerase / DNA Binding / Transferase-Antibiotic complex / TRANSFERASE

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