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-Structure paper
Title | Discovery of Novel Small-Molecule Inhibitors of BRD4 Using Structure-Based Virtual Screening. |
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Journal, issue, pages | J. Med. Chem., Vol. 56, Page 8073-8088, Year 2013 |
Publish date | Aug 27, 2013 (structure data deposition date) |
Authors | Vidler, L.R. / Filippakopoulos, P. / Fedorov, O. / Picaud, S. / Martin, S. / Tomsett, M. / Woodward, H. / Brown, N. / Knapp, S. / Hoelder, S. |
External links | J. Med. Chem. / PubMed:24090311 |
Methods | X-ray diffraction |
Resolution | 1.72 - 1.85 Å |
Structure data | PDB-4men: PDB-4meo: PDB-4mep: PDB-4meq: |
Chemicals | ChemComp-EDO: ChemComp-25K: ChemComp-HOH: ChemComp-25V: ChemComp-DMS: ChemComp-24Y: ChemComp-25O: |
Source |
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Keywords | TRANSCRIPTION/TRANSCRIPTION inhibitor / BRD4 / CAP / HUNK1 / MCAP / Mitotic chromosome associated protein / BRD / Small molecule inhibitor / Structural Genomics COnsortium / SGC / TRANSCRIPTION-TRANSCRIPTION inhibitor complex |