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TitleStaurosporine-derived inhibitors broaden the scope of analog-sensitive kinase technology.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 135, Page 18153-18159, Year 2013
Publish dateAug 21, 2013 (structure data deposition date)
AuthorsLopez, M.S. / Choy, J.W. / Peters, U. / Sos, M.L. / Morgan, D.O. / Shokat, K.M.
External linksJ. Am. Chem. Soc. / PubMed:24171479
MethodsX-ray diffraction
Resolution2.73 Å
Structure data

PDB-4mcv:
Star 12 bound to analog-sensitive Src kinase
Method: X-RAY DIFFRACTION / Resolution: 2.73 Å

Chemicals

ChemComp-29K:
(7S)-12-(4-aminobutyl)-7-(2-methylpropyl)-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one

Source
  • gallus gallus (chicken)
KeywordsTRANSFERASE/TRANSFERASE INHIBITOR / Kinase Domain / Tyrosine Kinase / TRANSFERASE-TRANSFERASE INHIBITOR complex

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