Movie
Controller
Structure viewers
About Yorodumi Papers
+Search query
-Structure paper
| Title | Thiazolopyridine Ureas as Novel Antitubercular Agents Acting through Inhibition of DNA Gyrase B. |
|---|---|
| Journal, issue, pages | J. Med. Chem., Vol. 56, Page 8834-8848, Year 2013 |
| Publish date | Aug 19, 2013 (structure data deposition date) |
 Authors | Kale, M.G. / Raichurkar, A. / Hameed, S.P. / Waterson, D. / McKinney, D. / Manjunatha, M.R. / Kranthi, U. / Koushik, K. / Jena, L.K. / Shinde, V. ...Kale, M.G. / Raichurkar, A. / Hameed, S.P. / Waterson, D. / McKinney, D. / Manjunatha, M.R. / Kranthi, U. / Koushik, K. / Jena, L.K. / Shinde, V. / Rudrapatna, S. / Barde, S. / Humnabadkar, V. / Madhavapeddi, P. / Basavarajappa, H. / Ghosh, A. / Ramya, V. / Guptha, S. / Sharma, S. / Vachaspati, P. / Kumar, K.N. / Giridhar, J. / Reddy, J. / Panduga, V. / Ganguly, S. / Ahuja, V. / Gaonkar, S. / Kumar, C.N. / Ogg, D. / Tucker, J.A. / Boriack-Sjodin, P.A. / de Sousa, S.M. / Sambandamurthy, V.K. / Ghorpade, S.R. |
 External links | J. Med. Chem. / PubMed:24088190 |
| Methods | X-ray diffraction |
| Resolution | 1.75 - 1.85 Å |
| Structure data |  PDB-4mb9:  PDB-4mbc: |
| Chemicals |  ChemComp-SO4:  ChemComp-28F:  ChemComp-HOH:  ChemComp-28G: |
| Source |
|
 Keywords | ISOMERASE/ISOMERASE INHIBITOR / ATP binding / structure-based drug design / antimicrobial / ISOMERASE-ISOMERASE INHIBITOR complex |
streptococcus pneumoniae (bacteria)