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TitleA phosphatidylinositol transfer protein integrates phosphoinositide signaling with lipid droplet metabolism to regulate a developmental program of nutrient stress-induced membrane biogenesis.
Journal, issue, pagesMol Biol Cell, Vol. 25, Page 712-727, Year 2014
Publish dateAug 14, 2013 (structure data deposition date)
AuthorsRen, J. / Pei-Chen Lin, C. / Pathak, M.C. / Temple, B.R. / Nile, A.H. / Mousley, C.J. / Duncan, M.C. / Eckert, D.M. / Leiker, T.J. / Ivanova, P.T. ...Ren, J. / Pei-Chen Lin, C. / Pathak, M.C. / Temple, B.R. / Nile, A.H. / Mousley, C.J. / Duncan, M.C. / Eckert, D.M. / Leiker, T.J. / Ivanova, P.T. / Myers, D.S. / Murphy, R.C. / Brown, H.A. / Verdaasdonk, J. / Bloom, K.S. / Ortlund, E.A. / Neiman, A.M. / Bankaitis, V.A.
External linksMol Biol Cell / PubMed:24403601
MethodsX-ray diffraction
Resolution1.928 Å
Structure data

PDB-4m8z:
Crystal Structure of SFH3, a phosphatidylinositol transfer protein that integrates phosphoinositide signaling with lipid droplet metabolism
Method: X-RAY DIFFRACTION / Resolution: 1.928 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • saccharomyces cerevisiae s288c (yeast)
KeywordsSIGNALING PROTEIN / Lipid droplets / Phosphoinositides / meiosis / CRAL TRIO / SEC14 / phospholipid signaling

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