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Structure paper

TitleX-ray structure of dopamine transporter elucidates antidepressant mechanism.
Journal, issue, pagesNature, Vol. 503, Page 85-90, Year 2013
Publish dateAug 6, 2013 (structure data deposition date)
AuthorsPenmatsa, A. / Wang, K.H. / Gouaux, E.
External linksNature / PubMed:24037379
MethodsX-ray diffraction
Resolution2.955 Å
Structure data

PDB-4m48:
X-ray structure of dopamine transporter elucidates antidepressant mechanism
Method: X-RAY DIFFRACTION / Resolution: 2.955 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-21B:
Nortriptyline / antidepressant*YM

ChemComp-CLR:
CHOLESTEROL

ChemComp-HOH:
WATER

Source
  • drosophila melanogaster (fruit fly)
  • mus musculus (house mouse)
KeywordsTRANSPORT PROTEIN / SLC6 / neurotransmitter transporter

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