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Title | Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies. |
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Journal, issue, pages | Immunity, Vol. 39, Page 245-258, Year 2013 |
Publish date | Jul 23, 2013 (structure data deposition date) |
Authors | Zhou, T. / Zhu, J. / Wu, X. / Moquin, S. / Zhang, B. / Acharya, P. / Georgiev, I.S. / Altae-Tran, H.R. / Chuang, G.Y. / Joyce, M.G. ...Zhou, T. / Zhu, J. / Wu, X. / Moquin, S. / Zhang, B. / Acharya, P. / Georgiev, I.S. / Altae-Tran, H.R. / Chuang, G.Y. / Joyce, M.G. / Do Kwon, Y. / Longo, N.S. / Louder, M.K. / Luongo, T. / McKee, K. / Schramm, C.A. / Skinner, J. / Yang, Y. / Yang, Z. / Zhang, Z. / Zheng, A. / Bonsignori, M. / Haynes, B.F. / Scheid, J.F. / Nussenzweig, M.C. / Simek, M. / Burton, D.R. / Koff, W.C. / Mullikin, J.C. / Connors, M. / Shapiro, L. / Nabel, G.J. / Mascola, J.R. / Kwong, P.D. |
External links | Immunity / PubMed:23911655 |
Methods | X-ray diffraction |
Resolution | 2.15 - 3 Å |
Structure data | PDB-4lsp: PDB-4lsq: PDB-4lsr: PDB-4lss: PDB-4lst: PDB-4lsu: PDB-4lsv: |
Chemicals | ChemComp-NAG: ChemComp-SO4: ChemComp-EDO: ChemComp-PEG: ChemComp-NA: ChemComp-HOH: ChemComp-CD: ChemComp-BU3: ChemComp-CL: ChemComp-EPE: ChemComp-IPA: ChemComp-IMD: |
Source |
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Keywords | viral protein/immune system / Neutralizing antibody VRC-CH31 / HIV envelope glycoprotein gp120 / viral protein-immune system complex / antibody antigen complex / Neutralizing antibody VRC01 / antibody antigen / Neutralizing antibody VRC-PG20 / Neutralizing antibody 3BNC117 |