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-Structure paper
Title | Structural, Biochemical, and Clinical Characterization of Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion Mutations in Lung Cancer. |
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Journal, issue, pages | Sci Transl Med, Vol. 5, Page 216ra177-216ra177, Year 2013 |
Publish date | Jul 19, 2013 (structure data deposition date) |
![]() | Yasuda, H. / Park, E. / Yun, C.H. / Sng, N.J. / Lucena-Araujo, A.R. / Yeo, W.L. / Huberman, M.S. / Cohen, D.W. / Nakayama, S. / Ishioka, K. ...Yasuda, H. / Park, E. / Yun, C.H. / Sng, N.J. / Lucena-Araujo, A.R. / Yeo, W.L. / Huberman, M.S. / Cohen, D.W. / Nakayama, S. / Ishioka, K. / Yamaguchi, N. / Hanna, M. / Oxnard, G.R. / Lathan, C.S. / Moran, T. / Sequist, L.V. / Chaft, J.E. / Riely, G.J. / Arcila, M.E. / Soo, R.A. / Meyerson, M. / Eck, M.J. / Kobayashi, S.S. / Costa, D.B. |
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Methods | X-ray diffraction |
Resolution | 2.5 - 3.526 Å |
Structure data | ![]() PDB-4lqm: ![]() PDB-4lrm: |
Chemicals | ![]() ChemComp-DJK: ![]() ChemComp-CL: ![]() ChemComp-HOH: ![]() ChemComp-YUN: |
Source |
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![]() | transferase/transferase inhibitor / EGFR / Kinase / PD168393 / 34-jab / transferase-transferase inhibitor complex |