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-Structure paper
Title | Dual inhibition of HIV-1 replication by integrase-LEDGF allosteric inhibitors is predominant at the post-integration stage. |
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Journal, issue, pages | Retrovirology, Vol. 10, Page 144-144, Year 2013 |
Publish date | Jun 30, 2013 (structure data deposition date) |
![]() | Le Rouzic, E. / Bonnard, D. / Chasset, S. / Bruneau, J.M. / Chevreuil, F. / Le Strat, F. / Nguyen, J. / Beauvoir, R. / Amadori, C. / Brias, J. ...Le Rouzic, E. / Bonnard, D. / Chasset, S. / Bruneau, J.M. / Chevreuil, F. / Le Strat, F. / Nguyen, J. / Beauvoir, R. / Amadori, C. / Brias, J. / Vomscheid, S. / Eiler, S. / Levy, N. / Delelis, O. / Deprez, E. / Saib, A. / Zamborlini, A. / Emiliani, S. / Ruff, M. / Ledoussal, B. / Moreau, F. / Benarous, R. |
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Methods | X-ray diffraction |
Resolution | 1.8 - 2.19 Å |
Structure data | ![]() PDB-4lh4: ![]() PDB-4lh5: |
Chemicals | ![]() ChemComp-MG: ![]() ChemComp-HOH: ![]() ChemComp-LF0: |
Source |
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![]() | TRANSFERASE / integrase / TRANSFERASE/TRANSFERASE INHIBITOR / TRANSFERASE-TRANSFERASE INHIBITOR complex |