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TitleAntigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells.
Journal, issue, pagesJ. Exp. Med., Vol. 210, Page 2305-2320, Year 2013
Publish dateJun 24, 2013 (structure data deposition date)
AuthorsReantragoon, R. / Corbett, A.J. / Sakala, I.G. / Gherardin, N.A. / Furness, J.B. / Chen, Z. / Eckle, S.B. / Uldrich, A.P. / Birkinshaw, R.W. / Patel, O. ...Reantragoon, R. / Corbett, A.J. / Sakala, I.G. / Gherardin, N.A. / Furness, J.B. / Chen, Z. / Eckle, S.B. / Uldrich, A.P. / Birkinshaw, R.W. / Patel, O. / Kostenko, L. / Meehan, B. / Kedzierska, K. / Liu, L. / Fairlie, D.P. / Hansen, T.H. / Godfrey, D.I. / Rossjohn, J. / McCluskey, J. / Kjer-Nielsen, L.
External linksJ. Exp. Med. / PubMed:24101382
MethodsX-ray diffraction
Resolution2.4 Å
Structure data

PDB-4lcw:
The structure of human MAIT TCR in complex with MR1-K43A-RL-6-Me-7OH
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-1VY:
1-deoxy-1-(7-hydroxy-6-methyl-2,4-dioxo-3,4-dihydropteridin-8(2H)-yl)-D-ribitol

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsMembrane Protein/Immune System / MHC Class I-related protein / MAIT T cell receptor / Vitamin B2 metabolites / Membrane Protein-Immune System complex

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