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-Structure paper
Title | Thienopyrimidine Bisphosphonate (ThPBP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase: Optimization and Characterization of the Mode of Inhibition. |
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Journal, issue, pages | J. Med. Chem., Vol. 56, Page 7939-7950, Year 2013 |
Publish date | Mar 25, 2013 (structure data deposition date) |
![]() | Leung, C.Y. / Park, J. / De Schutter, J.W. / Sebag, M. / Berghuis, A.M. / Tsantrizos, Y.S. |
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Methods | X-ray diffraction |
Resolution | 2.55 - 2.8 Å |
Structure data | ![]() PDB-4jvj: ![]() PDB-4l2x: |
Chemicals | ![]() ChemComp-1MV: ![]() ChemComp-SO4: ![]() ChemComp-MG: ![]() ChemComp-HOH: ![]() ChemComp-YL2: ![]() ChemComp-POP: |
Source |
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![]() | TRANSFERASE/TRANSFERASE INHIBITOR / TRANSFERASE-TRANSFERASE INHIBITOR complex |