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| Title | Characterization of selective exosite-binding inhibitors of matrix metalloproteinase 13 that prevent articular cartilage degradation in vitro. |
|---|---|
| Journal, issue, pages | J. Med. Chem., Vol. 57, Page 9598-9611, Year 2014 |
| Publish date | Jun 2, 2013 (structure data deposition date) |
Authors | Spicer, T.P. / Jiang, J. / Taylor, A.B. / Choi, J.Y. / Hart, P.J. / Roush, W.R. / Fields, G.B. / Hodder, P.S. / Minond, D. |
External links | J. Med. Chem. / PubMed:25330343 |
| Methods | X-ray diffraction |
| Resolution | 1.66 Å |
| Structure data | ![]() PDB-4l19: |
| Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-CA: ![]() ChemComp-FMT: ![]() ChemComp-1UA: ![]() ChemComp-GOL: ![]() ChemComp-HOH: |
| Source |
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Keywords | HYDROLASE/HYDROLASE INHIBITOR / metalloprotease / hydrolase / MMP-13 / collagenase / exosite inhibitor / HYDROLASE-HYDROLASE INHIBITOR complex |
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homo sapiens (human)
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