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TitleCrystal structure of a complex of human chymase with its benzimidazole derived inhibitor
Journal, issue, pagesJ. SYNCHROTRON RADIAT., Vol. 20, Page 914-918, Year 2013
Publish dateMay 12, 2013 (structure data deposition date)
AuthorsMatsumoto, Y. / Kakuda, S. / Koizumi, M. / Mizuno, T. / Muroga, Y. / Kawamura, T. / Takimoto-Kamimura, M.
External linksJ. SYNCHROTRON RADIAT. / PubMed:24121339
MethodsX-ray diffraction
Resolution2.8 Å
Structure data

PDB-4kp0:
Crystal Structure of the human Chymase with TJK002
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-KPK:
4-({1-[(4-methyl-1-benzothiophen-3-yl)methyl]-1H-benzimidazol-2-yl}sulfanyl)butanoic acid

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / Hydrolase / Protease / Serine protease / benzimidazole / HYDROLASE-HYDROLASE INHIBITOR complex

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