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-Structure paper
Title | Highly Potent HIV-1 Protease Inhibitors with Novel Tricyclic P2 Ligands: Design, Synthesis, and Protein-Ligand X-ray Studies. |
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Journal, issue, pages | J. Med. Chem., Vol. 56, Page 6792-6802, Year 2013 |
Publish date | Apr 23, 2013 (structure data deposition date) |
Authors | Ghosh, A.K. / Parham, G.L. / Martyr, C.D. / Nyalapatla, P.R. / Osswald, H.L. / Agniswamy, J. / Wang, Y.F. / Amano, M. / Weber, I.T. / Mitsuya, H. |
External links | J. Med. Chem. / PubMed:23947685 |
Methods | X-ray diffraction |
Resolution | 1.29 Å |
Structure data | PDB-4kb9: |
Chemicals | ChemComp-G79: ChemComp-CL: ChemComp-ACT: ChemComp-NA: ChemComp-GOL: ChemComp-HOH: |
Source |
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Keywords | Hydrolase/Hydrolase Inhibitor / spartic acid protease / HIV-1 protease inhibitor GRL-0739A / a Novel Tricyclic P2-ligand / Hydrolase-Hydrolase Inhibitor complex |