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-Structure paper
Title | Discovery of Potent, Selective Chymase Inhibitors via Fragment Linking Strategies. |
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Journal, issue, pages | J. Med. Chem., Vol. 56, Page 4465-4481, Year 2013 |
Publish date | Apr 9, 2013 (structure data deposition date) |
Authors | Taylor, S.J. / Padyana, A.K. / Abeywardane, A. / Liang, S. / Hao, M.H. / De Lombaert, S. / Proudfoot, J. / Farmer, B.S. / Li, X. / Collins, B. ...Taylor, S.J. / Padyana, A.K. / Abeywardane, A. / Liang, S. / Hao, M.H. / De Lombaert, S. / Proudfoot, J. / Farmer, B.S. / Li, X. / Collins, B. / Martin, L. / Albaugh, D.R. / Hill-Drzewi, M. / Pullen, S.S. / Takahashi, H. |
External links | J. Med. Chem. / PubMed:23659209 |
Methods | X-ray diffraction |
Resolution | 1.5 - 2.3 Å |
Structure data | PDB-4k2y: PDB-4k5z: PDB-4k60: PDB-4k69: |
Chemicals | ChemComp-ZN: ChemComp-NAG: ChemComp-ES2: ChemComp-HOH: ChemComp-1P7: ChemComp-1P8: ChemComp-1P9: |
Source |
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Keywords | HYDROLASE/HYDROLASE INHIBITOR / serine protease / glycosylated / Mast cells / secreted / HYDROLASE-HYDROLASE INHIBITOR complex |