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-Structure paper
| Title | Development of new deoxycytidine kinase inhibitors and noninvasive in vivo evaluation using positron emission tomography. |
|---|---|
| Journal, issue, pages | J. Med. Chem., Vol. 56, Page 6696-6708, Year 2013 |
| Publish date | Mar 12, 2013 (structure data deposition date) |
 Authors | Murphy, J.M. / Armijo, A.L. / Nomme, J. / Lee, C.H. / Smith, Q.A. / Li, Z. / Campbell, D.O. / Liao, H.I. / Nathanson, D.A. / Austin, W.R. ...Murphy, J.M. / Armijo, A.L. / Nomme, J. / Lee, C.H. / Smith, Q.A. / Li, Z. / Campbell, D.O. / Liao, H.I. / Nathanson, D.A. / Austin, W.R. / Lee, J.T. / Darvish, R. / Wei, L. / Wang, J. / Su, Y. / Damoiseaux, R. / Sadeghi, S. / Phelps, M.E. / Herschman, H.R. / Czernin, J. / Alexandrova, A.N. / Jung, M.E. / Lavie, A. / Radu, C.G. |
 External links | J. Med. Chem. / PubMed:23947754 |
| Methods | X-ray diffraction |
| Resolution | 1.89 - 1.94 Å |
| Structure data |  PDB-4jlk:  PDB-4l5b: |
| Chemicals |  ChemComp-UDP:  ChemComp-1NO:  ChemComp-HOH:  ChemComp-1UX: |
| Source |
|
 Keywords | transferase/transferase inhibitor / phosphoryl transfer / phosphorylation / kinase / transferase-transferase inhibitor complex / deoxycytidine kinase |
homo sapiens (human)