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-Structure paper
Title | Structural analysis of the positive AMPA receptor modulators CX516 and Me-CX516 in complex with the GluA2 ligand-binding domain |
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Journal, issue, pages | Acta Crystallogr. ,Sect. D, Vol. 69, Page 1645-1652, Year 2013 |
Publish date | Jan 28, 2013 (structure data deposition date) |
Authors | Krintel, C. / Harpsoe, K. / Zachariassen, L.G. / Peters, D. / Frydenvang, K. / Pickering, D.S. / Gajhede, M. / Kastrup, J.S. |
External links | Acta Crystallogr. ,Sect. D / PubMed:23999288 |
Methods | X-ray diffraction |
Resolution | 1.72 - 2 Å |
Structure data | PDB-4iy5: PDB-4iy6: |
Chemicals | ChemComp-GLU: ChemComp-SO4: ChemComp-GOL: ChemComp-CL: ChemComp-CX5: ChemComp-HOH: ChemComp-MQR: ChemComp-MQS: |
Source |
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Keywords | MEMBRANE PROTEIN / AMPA receptor ligand-binding domain / GLUA2 S1S2J-L483Y-N754S / CX516 / ALLOSTERIC MODULATION / ME-CX516 |