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-Structure paper
Title | Stabilization of Physical RAF/14-3-3 Interaction by Cotylenin A as Treatment Strategy for RAS Mutant Cancers. |
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Journal, issue, pages | Acs Chem. Biol., Vol. 8, Page 1869-1875, Year 2013 |
Publish date | Dec 13, 2012 (structure data deposition date) |
Authors | Molzan, M. / Kasper, S. / Roglin, L. / Skwarczynska, M. / Sassa, T. / Inoue, T. / Breitenbuecher, F. / Ohkanda, J. / Kato, N. / Schuler, M. / Ottmann, C. |
External links | Acs Chem. Biol. / PubMed:23808890 |
Methods | X-ray diffraction |
Resolution | 1.7 - 2.2 Å |
Structure data | PDB-4iea: PDB-4ihl: |
Chemicals | ChemComp-HOH: ChemComp-K: ChemComp-1F5: |
Source |
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Keywords | PEPTIDE BINDING PROTEIN / 14-3-3 FOLD / RAF / ALL ALPHA-HELICAL / ADAPTER PROTEIN / PROTEIN-PROTEIN INTERACTION |