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-Structure paper
Title | Allosteric integrase inhibitor potency is determined through the inhibition of HIV-1 particle maturation. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 110, Page 8690-8695, Year 2013 |
Publish date | Dec 11, 2012 (structure data deposition date) |
![]() | Jurado, K.A. / Wang, H. / Slaughter, A. / Feng, L. / Kessl, J.J. / Koh, Y. / Wang, W. / Ballandras-Colas, A. / Patel, P.A. / Fuchs, J.R. ...Jurado, K.A. / Wang, H. / Slaughter, A. / Feng, L. / Kessl, J.J. / Koh, Y. / Wang, W. / Ballandras-Colas, A. / Patel, P.A. / Fuchs, J.R. / Kvaratskhelia, M. / Engelman, A. |
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Methods | X-ray diffraction |
Resolution | 1.87 Å |
Structure data | ![]() PDB-4id1: |
Chemicals | ![]() ChemComp-LF0: ![]() ChemComp-SO4: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE/HYDROLASE INHIBITOR / HIV Integrase / CCD / DDE motif / dimer interface / allosteric inhibitor / quinoline / HYDROLASE-HYDROLASE INHIBITOR complex |