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Structure paper

TitleFirst structural evidence of sequestration of mRNA cap structures by type 1 ribosome inactivating protein from Momordica balsamina.
Journal, issue, pagesProteins, Vol. 81, Page 896-905, Year 2013
Publish dateApr 12, 2012 (structure data deposition date)
AuthorsKushwaha, G.S. / Yamini, S. / Kumar, M. / Sinha, M. / Kaur, P. / Sharma, S. / Singh, T.P.
External linksProteins / PubMed:23280611
MethodsX-ray diffraction
Resolution1.75 - 2.65 Å
Structure data

PDB-4emf:
Crystal structure of the complex of type I Ribosome inactivating protein in complex with 7n-methyl-8-hydroguanosine-5-p-diphosphate at 1.77 A
Method: X-RAY DIFFRACTION / Resolution: 1.77 Å

PDB-4emr:
Crystal Structure determination of type1 ribosome inactivating protein complexed with 7-methylguanosine-triphosphate at 1.75A
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

PDB-4i47:
Crystal structure of the Ribosome inactivating protein complexed with methylated guanine
Method: X-RAY DIFFRACTION / Resolution: 2.65 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-M7G:
7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE

ChemComp-HOH:
WATER

ChemComp-MGP:
7-METHYL-GUANOSINE-5'-TRIPHOSPHATE

ChemComp-MY6:
2-amino-7-methyl-1,7-dihydro-6H-purin-6-one

Source
  • momordica balsamina (balsam apple)
KeywordsHYDROLASE / Ligand binding / Ribosome inactivating protein / Complex hydrolase / 7-mgtp / RIP complex / N7-methylated guanine

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