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Structure paper

TitleStructures of Streptococcus pneumoniae PiaA and Its Complex with Ferrichrome Reveal Insights into the Substrate Binding and Release of High Affinity Iron Transporters
Journal, issue, pagesPlos One, Vol. 8, Page e71451-e71451, Year 2013
Publish dateOct 18, 2012 (structure data deposition date)
AuthorsCheng, W. / Li, Q. / Jiang, Y.-L. / Zhou, C.-Z. / Chen, Y.
External linksPlos One / PubMed:23951167
MethodsX-ray diffraction
Resolution2 - 2.7 Å
Structure data

PDB-4hmo:
Crystal structure of streptococcus pneumoniae TIGR4 PiaA in complex with Bis-tris propane
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-4hmp:
Crystal structure of iron uptake ABC transporter substrate-binding protein PiaA from Streptococcus pneumoniae TIGR4
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-4hmq:
Crystal structure of streptococcus pneumoniae TIGR4 PiaA in complex with ferrichrome
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-B3P:
2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-HOH:
WATER

ChemComp-CD:
Unknown entry

ChemComp-PG4:
TETRAETHYLENE GLYCOL / precipitant*YM

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-FCE:
FERRICHROME

ChemComp-CL:
Unknown entry

ChemComp-PGE:
TRIETHYLENE GLYCOL

Source
  • streptococcus pneumoniae (bacteria)
KeywordsTRANSPORT PROTEIN / class III substrate binding protein / ALPHA AND BETA PROTEIN / PERIPLASMIC BINDING PROTEIN TYPE III FOLD / iron uptake ABC transport system substrate binding protein / hydroxamate siderophore / membrane-anchored lipoprotein / iron uptake ABC transporter system substrate-binding protein / iron uptake ABC transporter system substrate binding protein / membrane anchored lipoprotein

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