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-Structure paper
Title | Identification and grafting of a unique peptide-binding site in the Fab framework of monoclonal antibodies. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 110, Page 17456-17461, Year 2013 |
Publish date | Aug 31, 2012 (structure data deposition date) |
Authors | Donaldson, J.M. / Zer, C. / Avery, K.N. / Bzymek, K.P. / Horne, D.A. / Williams, J.C. |
External links | Proc. Natl. Acad. Sci. USA / PubMed:24101516 |
Methods | X-ray diffraction |
Resolution | 1.95 - 2.24 Å |
Structure data | PDB-4gw1: PDB-4gw5: PDB-4hjg: PDB-4hkz: PDB-4ioi: |
Chemicals | ChemComp-PO4: ChemComp-HOH: ChemComp-CL: |
Source |
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Keywords | IMMUNE SYSTEM / IgG / EGFR / monoclonal antibody / cancer therapeutic / cancer immunotherapy |