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-Structure paper
Title | Erlotinib binds both inactive and active conformations of the EGFR tyrosine kinase domain. |
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Journal, issue, pages | Biochem. J., Vol. 448, Page 417-423, Year 2012 |
Publish date | Oct 13, 2012 (structure data deposition date) |
Authors | Park, J.H. / Liu, Y. / Lemmon, M.A. / Radhakrishnan, R. |
External links | Biochem. J. / PubMed:23101586 |
Methods | X-ray diffraction |
Resolution | 2.75 Å |
Structure data | PDB-4hjo: |
Chemicals | ChemComp-AQ4: ChemComp-HOH: |
Source |
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Keywords | TRANSFERASE/TRANSFERASE INHIBITOR / Inactive Tyrosine Kinase Domain / TRANSFERASE-TRANSFERASE INHIBITOR complex |