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-Structure paper
Title | Ligand modifications to reduce the relative resistance of multi-drug resistant HIV-1 protease. |
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Journal, issue, pages | Bioorg. Med. Chem., Vol. 21, Page 7430-7434, Year 2013 |
Publish date | Sep 5, 2012 (structure data deposition date) |
Authors | Dewdney, T.G. / Wang, Y. / Liu, Z. / Sharma, S.K. / Reiter, S.J. / Brunzelle, J.S. / Kovari, I.A. / Woster, P.M. / Kovari, L.C. |
External links | Bioorg. Med. Chem. / PubMed:24128815 |
Methods | X-ray diffraction |
Resolution | 2.05 - 2.27 Å |
Structure data | PDB-4gye: PDB-4gzf: |
Chemicals | ChemComp-HOH: |
Source |
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Keywords | HYDROLASE/HYDROLASE INHIBITOR / Multi-drug resistance / Protease inhibitor / Drug resistance / Substrate peptide / HYDROLASE-HYDROLASE INHIBITOR complex / substrate peptides |