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-Structure paper
Title | Multisubstituted quinoxalines and pyrido[2,3-d]pyrimidines: Synthesis and SAR study as tyrosine kinase c-Met inhibitors. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 22, Page 6368-6372, Year 2012 |
Publish date | Aug 5, 2012 (structure data deposition date) |
![]() | Wu, K. / Ai, J. / Liu, Q. / Chen, T. / Zhao, A. / Peng, X. / Wang, Y. / Ji, Y. / Yao, Q. / Xu, Y. ...Wu, K. / Ai, J. / Liu, Q. / Chen, T. / Zhao, A. / Peng, X. / Wang, Y. / Ji, Y. / Yao, Q. / Xu, Y. / Geng, M. / Zhang, A. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.27 - 2.423 Å |
Structure data | ![]() PDB-4gg5: ![]() PDB-4gg7: |
Chemicals | ![]() ChemComp-0J3: ![]() ChemComp-HOH: ![]() ChemComp-0J8: |
Source |
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![]() | TRANSFERASE/TRANSFERASE INHIBITOR / CMET inhibitor / TRANSFERASE-TRANSFERASE INHIBITOR complex / c-MET inhibitor |