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-Structure paper
Title | On the structural basis and design guidelines for type II topoisomerase-targeting anticancer drugs |
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Journal, issue, pages | Nucleic Acids Res., Vol. 41, Page 10630-10640, Year 2013 |
Publish date | Jul 10, 2012 (structure data deposition date) |
Authors | Wu, C.C. / Li, Y.C. / Wang, Y.R. / Li, T.K. / Chan, N.L. |
External links | Nucleic Acids Res. / PubMed:24038465 |
Methods | X-ray diffraction |
Resolution | 2.3 - 2.7 Å |
Structure data | PDB-4g0u: PDB-4g0v: PDB-4g0w: PDB-4j3n: |
Chemicals | ChemComp-MG: ChemComp-ASW: ChemComp-HOH: ChemComp-MIX: ChemComp-AKE: |
Source |
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Keywords | ISOMERASE/DNA/ISOMERASE INHIBITOR / TOPRIM domain / winged-helix domain / coiled-coil domain / DNA-binding and cleavage / nucleus / ISOMERASE-DNA-ISOMERASE INHIBITOR complex / ISOMERASE/DNA / DNA BINDING AND CLEAVAGE / ISOMERASE-DNA COMPLEX |