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TitleStructure of the Pentameric Ligand-Gated Ion Channel GLIC Bound with Anesthetic Ketamine.
Journal, issue, pagesStructure, Vol. 20, Page 1463-1469, Year 2012
Publish dateMay 17, 2012 (structure data deposition date)
AuthorsPan, J. / Chen, Q. / Willenbring, D. / Mowrey, D. / Kong, X.P. / Cohen, A. / Divito, C.B. / Xu, Y. / Tang, P.
External linksStructure / PubMed:22958642
MethodsX-ray diffraction
Resolution2.99 Å
Structure data

PDB-4f8h:
X-ray Structure of the Anesthetic Ketamine Bound to the GLIC Pentameric Ligand-gated Ion Channel
Method: X-RAY DIFFRACTION / Resolution: 2.99 Å

Chemicals

ChemComp-RKE:
(R)-ketamine

ChemComp-LMD:
tetradecyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside

ChemComp-PC1:
1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE / phospholipid*YM

ChemComp-HOH:
WATER

Source
  • gloeobacter violaceus (bacteria)
KeywordsTRANSPORT PROTEIN / ketamine / pentameric ligand-gated ion channel / ion channel / anesthetics

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