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Structure paper

TitleCharacterization of molecular determinants of the conformational stability of macrophage migration inhibitory factor: leucine 46 hydrophobic pocket.
Journal, issue, pagesPlos One, Vol. 7, Page e45024-e45024, Year 2012
Publish dateApr 24, 2012 (structure data deposition date)
AuthorsEl-Turk, F. / Fauvet, B. / Ashrafi, A. / Ouertatani-Sakouhi, H. / Cho, M.K. / Neri, M. / Cascella, M. / Rothlisberger, U. / Pojer, F. / Zweckstetter, M. / Lashuel, H.
External linksPlos One / PubMed:23028743
MethodsX-ray diffraction
Resolution1.61 - 1.7 Å
Structure data

PDB-4etg:
Crystal Structure of MIF L46G mutant
Method: X-RAY DIFFRACTION / Resolution: 1.61 Å

PDB-4eui:
Crystal Structure of MIF L46F mutant
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-4evg:
Crystal Structure of MIF L46A mutant
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsISOMERASE / Keto-enol tautomerase

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