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-Structure paper
Title | FRAX597, a Small Molecule Inhibitor of the p21-activated Kinases, Inhibits Tumorigenesis of Neurofibromatosis Type 2 (NF2)-associated Schwannomas. |
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Journal, issue, pages | J. Biol. Chem., Vol. 288, Page 29105-29114, Year 2013 |
Publish date | Apr 18, 2012 (structure data deposition date) |
![]() | Licciulli, S. / Maksimoska, J. / Zhou, C. / Troutman, S. / Kota, S. / Liu, Q. / Duron, S. / Campbell, D. / Chernoff, J. / Field, J. ...Licciulli, S. / Maksimoska, J. / Zhou, C. / Troutman, S. / Kota, S. / Liu, Q. / Duron, S. / Campbell, D. / Chernoff, J. / Field, J. / Marmorstein, R. / Kissil, J.L. |
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Methods | X-ray diffraction |
Resolution | 2.01 Å |
Structure data | ![]() PDB-4eqc: |
Chemicals | ![]() ChemComp-XR1: ![]() ChemComp-CL: ![]() ChemComp-HOH: |
Source |
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![]() | transferase/transferase inhibitor / Serine/threonine kinase / phosphorylation / ATP-binding / transferase-transferase inhibitor complex |