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-Structure paper
Title | New Class of HIV-1 Integrase (IN) Inhibitors with a Dual Mode of Action. |
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Journal, issue, pages | J. Biol. Chem., Vol. 287, Page 21189-21203, Year 2012 |
Publish date | Mar 6, 2012 (structure data deposition date) |
Authors | Tsiang, M. / Jones, G.S. / Niedziela-Majka, A. / Kan, E. / Lansdon, E.B. / Huang, W. / Hung, M. / Samuel, D. / Novikov, N. / Xu, Y. ...Tsiang, M. / Jones, G.S. / Niedziela-Majka, A. / Kan, E. / Lansdon, E.B. / Huang, W. / Hung, M. / Samuel, D. / Novikov, N. / Xu, Y. / Mitchell, M. / Guo, H. / Babaoglu, K. / Liu, X. / Geleziunas, R. / Sakowicz, R. |
External links | J. Biol. Chem. / PubMed:22535962 |
Methods | X-ray diffraction |
Resolution | 1.9 - 2 Å |
Structure data | PDB-4e1m: PDB-4e1n: |
Chemicals | ChemComp-TQ2: ChemComp-HOH: ChemComp-TQX: |
Source |
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Keywords | TRANSFERASE/TRANSFERASE INHIBITOR / HIV / integrase / TRANSFERASE-TRANSFERASE INHIBITOR complex / HIV-1 |