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-Structure paper
| Title | An aminoquinazoline inhibitor of the essential bacterial cell wall synthetic enzyme GlmU has a unique non-protein-kinase-like binding mode. |
|---|---|
| Journal, issue, pages | Biochem. J., Vol. 446, Page 405-413, Year 2012 |
| Publish date | Mar 6, 2012 (structure data deposition date) |
Authors | Larsen, N.A. / Nash, T.J. / Morningstar, M. / Shapiro, A.B. / Joubran, C. / Blackett, C.J. / Patten, A.D. / Boriack-Sjodin, P.A. / Doig, P. |
External links | Biochem. J. / PubMed:22721802 |
| Methods | X-ray diffraction |
| Resolution | 2 Å |
| Structure data | ![]() PDB-4e1k: |
| Chemicals | ![]() ChemComp-SO4: ![]() ChemComp-PG4: ![]() ChemComp-0N5: ![]() ChemComp-HOH: |
| Source |
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Keywords | TRANSFERASE/TRANSFERASE INHIBITOR / peptidoglycan synthesis / cell shape / metal-binding / cell wall biogenesis/degradation / multifunctional enzyme / acyltransferase / uridyltransferase / Nucleotidyl transferase / TRANSFERASE-TRANSFERASE INHIBITOR complex |
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haemophilus influenzae (bacteria)
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