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TitleA Binding Site for Nonsteroidal Anti-inflammatory Drugs in Fatty Acid Amide Hydrolase.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 135, Page 22-25, Year 2013
Publish dateFeb 9, 2012 (structure data deposition date)
AuthorsBertolacci, L. / Romeo, E. / Veronesi, M. / Magotti, P. / Albani, C. / Dionisi, M. / Lambruschini, C. / Scarpelli, R. / Cavalli, A. / De Vivo, M. ...Bertolacci, L. / Romeo, E. / Veronesi, M. / Magotti, P. / Albani, C. / Dionisi, M. / Lambruschini, C. / Scarpelli, R. / Cavalli, A. / De Vivo, M. / Piomelli, D. / Garau, G.
External linksJ. Am. Chem. Soc. / PubMed:23240907
MethodsX-ray diffraction
Resolution2.25 Å
Structure data

PDB-4do3:
Structure of FAAH with a non-steroidal anti-inflammatory drug
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-OHO:
CYCLOHEXANE AMINOCARBOXYLIC ACID

ChemComp-0LA:
(2S)-2-(6-chloro-9H-carbazol-2-yl)propanoic acid

ChemComp-HOH:
WATER

Source
  • rattus norvegicus (Norway rat)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / AMIDASE / HYDROLASE / ANANDAMIDE / NSAID / DRUG / COX / INHIBITOR / INFLAMMATION / PAIN / HYDROLASE-HYDROLASE INHIBITOR complex

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