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TitleX-ray Crystal Structure of 28-O-Methylrapamycin complexed with FKBP12: Is the Cyclohexyl Moiety Part of the Effector Domain of Rapamycin?
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 118, Page 5857-5861, Year 1996
Publish dateJan 27, 2012 (structure data deposition date)
AuthorsKallen, J. / Sedrani, R. / Cottens, S.
External linksJ. Am. Chem. Soc. / Search PubMed
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-4dh0:
X-ray Crystal Structure of 28-O-Methylrapamycin complexed with FKBP12: Is the Cyclohexyl Moiety Part of the Effector Domain of Rapamycin?
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-MR8:
28-O-Methylrapamycin

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsISOMERASE/IMMUNOSUPPRESSANT / peptidyl-prolyl cis-trans isomerase / ISOMERASE-IMMUNOSUPPRESSANT complex

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