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Structure paper

TitleStructural Basis for Hijacking Siderophore Receptors by Antimicrobial Lasso Peptides.
Journal, issue, pagesNat. Chem. Biol., Vol. 10, Page 340-, Year 2014
Publish dateMar 17, 2014 (structure data deposition date)
AuthorsMathavan, I. / Zirah, S. / Mehmood, S. / Choudhury, H.G. / Goulard, C. / Li, Y. / Robinson, C.V. / Rebuffat, S. / Beis, K.
External linksNat. Chem. Biol. / PubMed:24705590
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-4cu4:
FhuA from E. coli in complex with the lasso peptide microcin J25 (MccJ25)
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-FTT:
3-HYDROXY-TETRADECANOIC ACID

ChemComp-DAO:
LAURIC ACID

ChemComp-MYR:
MYRISTIC ACID

ChemComp-LDA:
LAURYL DIMETHYLAMINE-N-OXIDE / LDAO, detergent*YM

ChemComp-3PH:
1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE

ChemComp-DPO:
DIPHOSPHATE

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

Source
  • escherichia coli str. k-12 substr. mg1655 (bacteria)
  • escherichia coli str. k-12 substr. mc4100 (bacteria)
KeywordsTRANSPORT PROTEIN/ANTIBIOTIC / TRANSPORT PROTEIN-ANTIBIOTIC COMPLEX / LIPOPOLYSACCHARIDE / DETERGENT

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