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TitleThe Discovery of Potent and Selective Non-Steroidal Glucocorticoid Receptor Modulators, Suitable for Inhalation.
Journal, issue, pagesBioorg. Med. Chem. Lett., Vol. 24, Page 2571-, Year 2014
Publish dateMar 7, 2014 (structure data deposition date)
AuthorsEdman, K. / Ahlgren, R. / Bengtsson, M. / Bladh, H. / Backstrom, S. / Dahmen, J. / Henriksson, K. / Hillertz, P. / Hulikal, V. / Jerre, A. ...Edman, K. / Ahlgren, R. / Bengtsson, M. / Bladh, H. / Backstrom, S. / Dahmen, J. / Henriksson, K. / Hillertz, P. / Hulikal, V. / Jerre, A. / Kinchin, L. / Kase, C. / Lepisto, M. / Mile, I. / Nilsson, S. / Smailagic, A. / Taylor, J. / Tjornebo, A. / Wissler, L. / Hansson, T.
External linksBioorg. Med. Chem. Lett. / PubMed:24755427
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-4csj:
The discovery of potent selective glucocorticoid receptor modulators, suitable for inhalation
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-NN7:
N-[(2S)-1-[[1-(4-fluorophenyl)indazol-4-yl]amino]propan-2-yl]-2,4,6-trimethyl-benzenesulfonamide

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / NUCLEAR HORMONE RECEPTOR / LIGAND COMPLEX / PEPTIDE COMPLEX

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