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Structure paper

TitleThe crystal structure of MPK38 in complex with OTSSP167, an orally administrative MELK selective inhibitor.
Journal, issue, pagesBiochem. Biophys. Res. Commun., Vol. 447, Page 7-11, Year 2014
Publish dateFeb 17, 2014 (structure data deposition date)
AuthorsCho, Y.S. / Kang, Y. / Kim, K. / Cha, Y.J. / Cho, H.S.
External linksBiochem. Biophys. Res. Commun. / PubMed:24657156
MethodsX-ray diffraction
Resolution2.57 Å
Structure data

PDB-4cqg:
The crystal structure of MPK38 in complex with OTSSP167, an orally- administrative MELK selective inhibitor
Method: X-RAY DIFFRACTION / Resolution: 2.57 Å

Chemicals

ChemComp-OT5:
1-[6-(3,5-dichloro-4-hydroxyphenyl)-4-({trans-4-[(dimethylamino)methyl]cyclohexyl}amino)-1,5-naphthyridin-3-yl]ethanone

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsTRANSFERASE

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