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-Structure paper
Title | Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents. |
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Journal, issue, pages | Nature, Vol. 384, Page 644-648, Year 1996 |
Publish date | Dec 17, 1996 (structure data deposition date) |
Authors | Kurumbail, R.G. / Stevens, A.M. / Gierse, J.K. / McDonald, J.J. / Stegeman, R.A. / Pak, J.Y. / Gildehaus, D. / Miyashiro, J.M. / Penning, T.D. / Seibert, K. ...Kurumbail, R.G. / Stevens, A.M. / Gierse, J.K. / McDonald, J.J. / Stegeman, R.A. / Pak, J.Y. / Gildehaus, D. / Miyashiro, J.M. / Penning, T.D. / Seibert, K. / Isakson, P.C. / Stallings, W.C. |
External links | Nature / PubMed:8967954 |
Methods | X-ray diffraction |
Resolution | 2.5 - 3 Å |
Structure data | PDB-1cx2: PDB-3pgh: PDB-4cox: PDB-5cox: PDB-6cox: |
Chemicals | ChemComp-NAG: ChemComp-HEM: ChemComp-S58: ChemComp-FLP: ChemComp-IMN: |
Source |
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Keywords | OXIDOREDUCTASE / PEROXIDASE / DIOXYGENASE / CYCLOOXYGENASE / NONSTEROIDAL ANTIINFLAMMATORY DRUGS / INFLAMMATION / ARTHRITIS / PROSTAGLANDIN / PROSTAGLANDIN SYNTHASE |