+Search query
-Structure paper
Title | Fragment-Based Discovery of 6-Azaindazoles as Inhibitors of Bacterial DNA Ligase. |
---|---|
Journal, issue, pages | Acs Med. Chem. Lett., Vol. 4, Page 1208-, Year 2013 |
Publish date | Oct 18, 2013 (structure data deposition date) |
Authors | Howard, S. / Amin, N. / Benowitz, A.B. / Chiarparin, E. / Cui, H. / Deng, X. / Heightman, T.D. / Holmes, D.J. / Hopkins, A. / Huang, J. ...Howard, S. / Amin, N. / Benowitz, A.B. / Chiarparin, E. / Cui, H. / Deng, X. / Heightman, T.D. / Holmes, D.J. / Hopkins, A. / Huang, J. / Jin, Q. / Kreatsoulas, C. / Martin, A.C.L. / Massey, F. / Mccloskey, L. / Mortenson, P.N. / Pathuri, P. / Tisi, D. / Williams, P.A. |
External links | Acs Med. Chem. Lett. / PubMed:24900632 |
Methods | X-ray diffraction |
Resolution | 1.88 - 2.01 Å |
Structure data | PDB-4cc5: PDB-4cc6: |
Chemicals | ChemComp-SO4: ChemComp-L5V: ChemComp-HOH: ChemComp-L5Y: |
Source |
|
Keywords | LIGASE / ANTIBIOTIC DESIGN / LIGA |