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| Title | Crystal Structures of Human Cholinesterases in Complex with Huprine W and Tacrine: Elements of Specificity for Anti-Alzheimer'S Drugs Targeting Acetyl- and Butyrylcholinesterase. |
|---|---|
| Journal, issue, pages | Biochem. J., Vol. 453, Page 393-, Year 2013 |
| Publish date | Oct 6, 2012 (structure data deposition date) |
Authors | Nachon, F. / Carletti, E. / Ronco, C. / Trovaslet, M. / Nicolet, Y. / Jean, L. / Renard, P. |
External links | Biochem. J. / PubMed:23679855 |
| Methods | X-ray diffraction |
| Resolution | 2.1 - 3.104 Å |
| Structure data | ![]() PDB-4bds: ![]() PDB-4bdt: |
| Chemicals | ![]() ChemComp-NAG: ![]() ChemComp-FUC: ![]() ChemComp-THA: ![]() ChemComp-GOL: ![]() ChemComp-SO4: ![]() ChemComp-CL: ![]() ChemComp-FPK: ![]() ChemComp-UNX: ![]() ChemComp-HOH: ![]() ChemComp-HUW: |
| Source |
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Keywords | HYDROLASE / NERVE TRANSMISSION / INHIBITIOR / ALPHA-BETA HYDROLASE / HYDROLASE/INHIBITOR / HYDROLASE-INHIBITOR COMPLEX / BUTYRYLCHOLINESTERASE / INHIBITION |
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homo sapiens (human)
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