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-Structure paper
Title | At13148 is a Novel, Oral Multi-Agc Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity. |
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Journal, issue, pages | Clin. Cancer Res., Vol. 18, Page 3912-, Year 2012 |
Publish date | Jun 12, 2012 (structure data deposition date) |
![]() | Yap, T.A. / Walton, M.I. / Grimshaw, K.M. / Te Poele, R.H. / Eve, P.D. / Valenti, M.R. / De Haven Brandon, A.K. / Martins, V. / Zetterlund, A. / Heaton, S.P. ...Yap, T.A. / Walton, M.I. / Grimshaw, K.M. / Te Poele, R.H. / Eve, P.D. / Valenti, M.R. / De Haven Brandon, A.K. / Martins, V. / Zetterlund, A. / Heaton, S.P. / Heinzmann, K. / Jones, P.S. / Feltell, R.E. / Reule, M. / Woodhead, S.J. / Davies, T.G. / Lyons, J.F. / Raynaud, F.I. / Eccles, S.A. / Workman, P. / Thompson, N.T. / Garrett, M.D. |
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Methods | X-ray diffraction |
Resolution | 1.9 Å |
Structure data | ![]() PDB-4axa: |
Chemicals | ![]() ChemComp-RKD: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSFERASE/TRANSFERASE INHIBITOR / TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX |