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-Structure paper
Title | Dissociation of Antibacterial Activity and Aminoglycoside Ototoxicity in the 4-Monosubstituted 2-Deoxystreptamine Apramycin. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 109, Page 10984-, Year 2012 |
Publish date | Apr 20, 2012 (structure data deposition date) |
Authors | Matt, T. / Ng, C.L. / Lang, K. / Sha, S.H. / Akbergenov, R. / Shcherbakov, D. / Meyer, M. / Duscha, S. / Xie, J. / Dubbaka, S.R. ...Matt, T. / Ng, C.L. / Lang, K. / Sha, S.H. / Akbergenov, R. / Shcherbakov, D. / Meyer, M. / Duscha, S. / Xie, J. / Dubbaka, S.R. / Perez-Fernandez, D. / Vasella, A. / Ramakrishnan, V. / Schacht, J. / Bottger, E.C. |
External links | Proc. Natl. Acad. Sci. USA / PubMed:22699498 |
Methods | X-ray diffraction |
Resolution | 3.5 Å |
Structure data | PDB-4aqy: |
Chemicals | ChemComp-MG: ChemComp-K: ChemComp-AM2: ChemComp-ZN: ChemComp-HOH: |
Source |
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Keywords | RIBOSOME / APRAMYCIN / TOXICITY |