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TitleCrystallographic Study of Novel Transthyretin Inhibitors: Unique Mechanism of Negative-Cooperativity between Two T4 Binding Sites
Journal, issue, pagesTo be Published
Publish dateDec 19, 2011 (structure data deposition date)
AuthorsTomar, D. / Khan, T. / Singh, R.R. / Mishra, S. / Gupta, S. / Surolia, A. / Salunke, D.M.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.8 Å
Structure data

PDB-4act:
CRYSTAL STRUCTURE OF TRANSTHYRETIN IN COMPLEX WITH LIGAND C-17
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-FT0:
3-hydroxy-4-phenoxybenzaldehyde

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSPORT PROTEIN / THYROXINE TRANSPORT PROTEIN / HORMONE / AMYLOIDOSIS INHIBITION

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